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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease lynch syndrome
Comorbidity C1140680|ovarian cancer
Sentences 9
PubMedID- 22808608 This is a maternal history of a 27-year-old woman sharing the destiny of her 48-year-old mother and 45-year-old aunt, both of which were suffering from lynch syndrome associated with ovarian cancer.
PubMedID- 23765559 Endometrial and ovarian cancer in women with lynch syndrome: update in screening and prevention.
PubMedID- 23730224 Endometrial and ovarian cancer in lynch syndrome.
PubMedID- 24023337 We report on a case of synchronous endometrial and ovarian cancer in a patient with lynch syndrome.
PubMedID- 24396821 Prophylactic hysterectomy and bilateral salpingo-oophorectomy are known to prevent endometrial and ovarian cancers in patients with lynch syndrome [10].
PubMedID- 21388660 Conclusion: the combined data from our cohorts demonstrate that ovarian cancer associated with lynch syndrome typically presents at young age as early-stage, non-serous tumors, which implicates that a family history of colorectal and endometrial cancer should be specifically considered in such cases.
PubMedID- 25279173 The lifetime risk for ovarian cancer in families with lynch syndrome is ~8%, which is lower than colorectal and endometrial cancers, and ovarian cancer is not listed in the amsterdam criteria ii.
PubMedID- 25342222 The impact of risk-reducing gynaecological surgery in premenopausal women at high risk of endometrial and ovarian cancer due to lynch syndrome.
PubMedID- 25093288 ovarian cancers associated with lynch syndrome are predominantly clear cell or endometrioid in histology.

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